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1.
Braz. j. oral sci ; 23: e243442, 2024. tab
Article in English | LILACS, BBO | ID: biblio-1537096

ABSTRACT

Aim: to evaluate the occurrence of maxillofacial infection cases, which were treated at local hospital, identifying the main risk factors that determine the need for hospitalization of patients and the factors associated with staying length. Methods: A retrospective review of 191 records of patients with maxillofacial infection of odontogenic origin was performed, statistically evaluated by frequency and percentage of involvement, p values (based on the chi-square test) and odds ratio with a 95% confidence interval. A p-value <0.05 was considered statistically significant. Results: Among all the 191 patients, 31 had some harmful habits, such as smokers (13%) and alcoholics (1%). In addition, 39 patients reported some general health problem, such as systemic arterial hypertension (8.3%), depression (6.8%), diabetes (3.6%) and some immunosuppression (1.57%). Involvement of infection in deep facial spaces was present, with 119 patients presenting a deeper infection (62.3%) and 72 patients a superficial infection (37.7%). The most prevalent clinical signs and symptoms in the initial evaluation were pain (91.1%) and edema (90.1%), followed by erythema/hyperemia (44.5%), trismus (37.7%), abscess (30.9%), cellulitis (27.7%), f istula (16.8%), fever (16.8%), dysphagia (11%), dehydration (9.9%), odynophagia (7.9% ) and dyspnea (3.7%). Pulp necrosis was considered a risk factor for treatment in a hospital environment (0.032) and root canal treatment decreases the risk of hospitalization (p=0.002). Considering the evaluated patients, 146 (76.4%) were admitted and 45 (37.7%) were not admitted for hospitalization after initial clinical evaluation. Conclusion: there is a high occurrence of maxillofacial infection cases of dental origin, considering that involvement of infection in deeper facial spaces, as well as presence of pain, edema, erythema/hyperemia, trismus, abscess, cellulitis and pulp necrosis, represent the main risk factors for hospitalization and staying length


Subject(s)
Signs and Symptoms , Medical Records , Risk Factors , Residence Time , Focal Infection, Dental , Hospitalization
2.
Rev Enferm UFPI ; 12(1): e3811, 2023-12-12. tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1523658

ABSTRACT

Objetivo: Analisar os fatores relacionados à COVID longa na população adulta do Brasil. Métodos: Estudo transversal analítico, do tipo web-survey, com abordagem quantitativa. A amostragem foi não probabilística, do tipo intencional, e incluiu 228 adultos brasileiros que testaram positivo para COVID-19. A coleta de dados ocorreu por meio de questionário online. Para verificar a associação entre variáveis qualitativas, utilizou-se o Teste Qui-quadrado ou Teste Exato de Fisher e, nas quantitativas, aplicou-se o Teste de Mann-Whitney com significância de 0,05. Resultados: Constatou-se que houve associação de variáveis sociodemográficas com a COVID longa. Observa-se maior média de idade entre aqueles em que persistiram os sintomas (p=0,041). A renda familiar daqueles com sintomas persistentes era inferior à dos indivíduos sem persistência (p=0,005). A prática de atividade física esteve associada a não persistência dos sintomas (p=0,024). A hipertensão arterial foi a comorbidade mais prevalente naqueles com sintomas persistentes (5,9%). No quadro clínico de COVID-19 associado à persistência dos sintomas, identificam-se calafrios (p-valor=0,009), cefaleia (p-valor=0,0027), tosse (p-valor=0,000), anosmia (p-valor=0,048), ageusia (p-valor=0,013), dispneia (p-valor=0,000) e diarreia (p-valor=0,018). sintoma de COVID longa mais prevalente foi a fadiga (62,89%). Conclusão: Idade e renda estiveram associadas à COVID longa. Praticar atividade física esteve associado a não persistência de sintomas. Descritores: COVID-19;COVID Longa; Sinais e Sintomas;Fatores de Risco; Brasil.


Objective:To analyze the factors related to long COVID in the adult population of Brazil. Methods:Analytical cross-sectional study, web-survey type, with quantitative approach. The sampling was non-probabilistic, of the intentional type, including 228 Brazilian adults who tested positive for COVID-19. Data collection took place through an online questionnaire. To verify the association between qualitative variables, the Chi-square test or Fisher's exact test was used and, in quantitative variables, the Mann-Whitneytest was applied with significance of 0.05.Results:It was observed that there was an association of sociodemographic variables with long COVID. A higher mean age was observed among those who persisted symptoms (p=0.041). The family income of those with persistent symptoms was lower than that of individualswithout persistence (p=0.005). The practice of physical activity was associated with the non-persistence of symptoms (p=0.024). Arterial hypertension was the most prevalent comorbidity in those with persistent symptoms (5.9%). In the clinical picture of COVID-19 associated with the persistence of symptoms, it is observed: chills (p-value=0.009), headache (p-value=0.0027), cough (p-value=0.000), anosmia (p-value=0.048), ageusia (p-value=0.013), dyspnea (p-value=0.000) and diarrhea (p-value=0.018). The most prevalent long COVID symptom was fatigue (62.89%).Conclusion:Age and income were associated with long COVID. Physical activity was associated with no persistence of symptoms. Descriptors: COVID-19; Long Covid; Signs and Symptoms; Risk Factors; Brazil


Subject(s)
Signs and Symptoms , Brazil , Risk Factors , COVID-19
3.
Rev. Ciênc. Saúde ; 13(3): 3-9, 20230921.
Article in English, Portuguese | LILACS | ID: biblio-1510411

ABSTRACT

A fibromialgia é uma condição crônica de etiologia desconhecida e desvinculada de marcadores laboratoriais específicos para diagnóstico, devido à pobre caracterização da etiopatogenia. Em geral, as alterações comuns à fibromialgia também são observadas em outras condições de dor crônica, tornando a patogênese controversa entre diferentes condições patológicas. A etiologia desconhecida dificulta o diagnóstico e, consequentemente, repercute em um tratamento não tão eficaz de pacientes com fibromialgia. A restauração de desordens sistêmicas confere amplo espectro de possibilidades terapêuticas com potencial de orientar profissionais a estabelecer metas e métodos de avaliação. Diante disso, essa revisão narrativa se volta para debater hipóteses etiológicas e fisiopatológicas no desenvolvimento da fibromialgia.


Fibromyalgia is a chronic condition of unknown etiology unrelated to specific laboratory markers for diagnosis because of poor etiopathogenesis. In general, the changes common to fibromyalgia are also seen in other chronic pain conditions, making the pathogenesis controversial among different pathological conditions. The unknown etiology makes the diagnosis difficult and consequently has repercussions on a not so effective treatment of patients with fibromyalgia. The restoration of systemic disorders provides a wide spectrum of therapeutic possibilities with the potential to guide professionals in establishing goals and evaluation methods. Therefore, this narrative review discusses the etiological and pathophysiological hypotheses involved in the development of fibromyalgia.


Subject(s)
Humans , Female , Signs and Symptoms , Diagnosis
5.
J. nurs. health ; 13(1): 13122461, abr. 2023.
Article in Portuguese | LILACS, BDENF | ID: biblio-1524518

ABSTRACT

Objetivo:avaliar a presença e intensidade dos sinais e sintomas de pacientes em cuidados paliativos nos três primeiros dias de internação. Método:estudo observacional, com pacientes adultos e idosos. Foi utilizado questionário para a coleta dos dados sociodemográficos e clínicos e um instrumento validado para a avaliação dos sinais e sintomas. Resultados:dentre os 50 participantes, a maioria é mulher (56%) com idade média de 66,7 anos e escolaridade de 6,1 anos. A principal doença de base foi câncer de pulmão (12%). Apresentaram elevados níveis de cansaço, sonolência, falta de apetite, depressão e ansiedade no primeiro dia de internação. No decorrer dos três dias de observação houve melhora em relação ao cansaço e à depressão e piora da sonolência. Conclusão:a assistência paliativa possui potencial para contribuir com o adequado manejo dos sintomas ao longo da internação, o que pode influenciar positivamente a qualidade de vida dos pacientes.


Objective:to evaluate the presence and intensity of signs and symptoms of patients in palliative care in the first three days of hospitalization. Method:observational, study with adult and elderly patients. A questionnaire was used to collect sociodemographic and clinical data and a validated instrument for the evaluation of signs and symptoms.Results:among the 50 participants, most are women (56%) with a mean age of 66.7 years and schooling of 6.1 years. The main underlying disease was lung cancer (12%). They presented high levels of tiredness, sleepiness, lack of appetite, depression, and anxiety on the first day of hospitalization. During the three days of observation, there was an improvement in terms of tiredness and depression and a worsening of sleepiness. Conclusion:palliative care has the potential to contribute to the adequate management of symptoms during hospitalization, which can positively influence patients' quality of life.


Objetivo:evaluar la presencia e intensidad de signos y síntomas de pacientes en cuidados paliativos en los tres primeros días de hospitalización. Método:estudio observacional, con pacientes, adultos y ancianos. Se utilizó cuestionario para recolectar datos socio demográficos, clínicos e instrumento validado para la evaluación de signos y síntomas. Resultados:entre los 50 participantes, la mayoría son mujeres (56%) con una edad media de 66,7 años y escolaridad de 6,1 años. La principal enfermedad de base fue el cáncer de pulmón (12%). Presentaron altos niveles de cansancio, somnolencia, inapetencia, depresión y ansiedad el primer día de hospitalización. Durante los tres días de observación, hubo una mejoría en términos de cansancio y depresión y un empeoramiento de la somnolencia. Conclusión:los cuidados paliativos tienen el potencial de contribuir al manejo adecuado de los síntomas durante la hospitalización, lo que puede influir positivamente en la calidad de vida de los pacientes.


Subject(s)
Palliative Care , Signs and Symptoms , Nursing , Hospitalization
6.
Acta neurol. colomb ; 39(1): 51-56, ene.-mar. 2023.
Article in Spanish | LILACS | ID: biblio-1429574

ABSTRACT

RESUMEN INTRODUCCIÓN: El diagnóstico oportuno del trastorno neurocognitivo es de los principales retos en la atención de los trastornos neurocognitivos. Por esto, se han generado estrategias para la detección preclínica de la enfermedad, entre ellas las destinadas a evaluar síntomas neuropsiquiátricos (NPS) como la escala Mild Behavior Impairment - Checklist (MBI-C). MÉTODOS: Inicialmente se realizó una búsqueda en BVSalud, Medline y PsycNet, luego se realizó una búsqueda en bola de nieve. Se incluyeron términos referentes a deterioro comportamental leve (abarcando los NPS en etapas tempranas), deterioro cognitivo leve y términos específicos del MBI-C. RESULTADOS: La presencia de NPS se asocia con un aumento en la incidencia anual de demencia. Al evaluarlos con MBI-C, su puntuación se correlaciona con biomarcadores como una mayor atrofia cortical, la presencia de la proteína β-amiloide, así como disminución en funciones ejecutivas como la capacidad de enfocar la atención y la memoria de trabajo. DISCUSIÓN: Los hallazgos en la literatura sugieren la utilidad de MBI-C como marcador de neurodegeneración en estadios previos a la demencia, esto mediante la evaluación de su capacidad predictiva de forma independiente y al compararla con otros biomarcadores. CONCLUSIONES: MBI-C supone ser un instrumento de fácil aplicabilidad e interpretación, sostenible e incluyente. Sin embargo, quedan vacíos sobre la pertinencia de esta escala, por lo que surge la necesidad de investigar este tema.


ABSTRACT INTRODUCTION: Early diagnosis of neurocognitive disorder is the main challenge of dementia health attention. Therefore, strategies for preclinical detection of the disease have been created, like those intended to evaluate neuropsychiatric symptoms (NPS), like the Mild Behavior Impairment - Checklist (MBI-C). METHODS: Research was performed in BVSalud, Medline, and Psynet. Then a snowball sampling was done. The terms included were mild behavioral impairment (included NPS in initial stages), mild cognitive impairment, and specific terms of MBI-C. RESULTS: The presence of NPS increase the incidence of dementia, with an annual conversion rate of 9%. About MBI-C, the score has been related to biomarkers like worse brain atrophy in patients with Parkinson's Disease and a positive relationship with the presence of B-amyloid protein. Also, Creese and cols. show that mild behavioral impairment (measured by MBI-C) is associated with a faster decrease in attention and working memory. DISCUSSION: MBI-C utility as a neurodegenerative marker has been demonstrated to detect cognitive, neuropsychiatry, and functional symptoms that may precede dementia by evaluating its predictive capacity alone and comparing it to other biomarkers. CONCLUSION: MBI-C is easy to apply and interpret, is sustainable and inclusive. However, there are still gaps in the relevance of the scale, so there is the need to continue investigating this topic.


Subject(s)
Behavioral Symptoms , Dementia , Cognitive Dysfunction , Signs and Symptoms , Neuropsychiatry , Forecasting
7.
Enferm. foco (Brasília) ; 14mar. 20, 2023. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1443159

ABSTRACT

Objetivo: Identificar as consequências da violência no trabalho sofridas por enfermeiros do atendimento pré-hospitalar. Métodos: Estudo transversal, descritivo, realizado com 67 enfermeiros de um serviço de atendimento pré-hospitalar do município do Rio de Janeiro, Brasil. Os dados foram analisados com a utilização da Janela de Johari. Resultados: Destacaram-se como consequências da violência no trabalho queixas de medo, estresse, ansiedade, insônia, irritabilidade, desmotivação laboral, taquicardia, dor de cabeça, tristeza, desânimo, hipertensão arterial, precordialgia, ganho de peso, necessidade de assistência psicológica e psiquiátrica com a prescrição de medicalização. Conclusão: A violência no trabalho do atendimento pré-hospitalar provoca consequências que envolvem as dimensões físicas e emocionais. Faz-se necessária a discussão e reflexão no plano institucional, com a participação dos profissionais, sobre as características do ambiente de trabalho, riscos, exposições, doenças relacionadas ao trabalho, nexo causal e as consequências da violência no trabalho. (AU)


Objective: Identify the consequences of violence at work suffered by nurses in pre-hospital care. Methods: This is a cross-sectional, descriptive study conducted with 67 nurses from a pre-hospital care service in the city of Rio de Janeiro, Brazil. The data were analyzed using the Johari's Window. Results: Complaints of fear, stress, anxiety, insomnia irritability, work demotivation, tachycardia, headache, sadness, discouragement, hypertension, precordialgia, weight gain, need for psychological and psychiatric care with the prescription of medicalization were highlighted as consequences of violence at work. Conclusion: Violence at work in pre-hospital care causes consequences that involve the physical and emotional dimensions. It is necessary to discuss and reflect at the institutional level, with the participation of professionals, on the characteristics of the work environment, risks, exposures, work-related diseases, causal link and the consequences of violence at work. (AU)


Objetivo: Identificar las consecuencias de la violencia en el trabajo que sufren los enfermeros en la atención prehospitalaria. Métodos: Estudio transversal y descriptivo realizado con 67 enfermeros de un servicio de atención prehospitalaria en la ciudad de Río de Janeiro, Brasil. Los datos fueron analizados usando la Ventana Johari. Resultados: Las quejas por miedo, estrés, ansiedad, insomnio, irritabilidad, desmotivación del trabajo, taquicardia, dolor de cabeza, tristeza, desánimo, hipertensión, precordialgia, aumento de peso, necesidad de atención psicológica y psiquiátrica con prescripción de medicalización se destacaron como consecuencias de la violencia en el trabajo. Conclusión: La violencia en el trabajo en la atención prehospitalaria causa consecuencias que involucran las dimensiones física y emocional. Es necesario discutir y reflexionar a nivel institucional, con la participación de los profesionales, sobre las características del entorno de trabajo, riesgos, exposiciones, enfermedades relacionadas con el trabajo, relación causal y consecuencias de la violencia en el trabajo. (AU)


Subject(s)
Workplace Violence , Signs and Symptoms , Occupational Health , Emergency Medical Services , Nurses
9.
Femina ; 51(3): 167-173, 20230331. Ilus, Tab
Article in Portuguese | LILACS | ID: biblio-1428729

ABSTRACT

Objetivo: Caracterizar as notificações de infecção por SARS-CoV-2 em gestantes em um município do sul de Santa Catarina. Métodos: Estudo transversal que avaliou as notificações de casos suspeitos de infecção por SARS-CoV-2 em gestantes no município de Tubarão, Santa Catarina, de março de 2020 a outubro de 2021. Coletaram-se os dados das fichas de notificação de infecção por SARS-CoV-2 da Fundação Municipal de Saúde e no Prontuário Eletrônico do Cidadão (PEC) das gestantes notificadas. A comparação da prevalência de confirmação segundo sintomas apresentados e características maternas foi realizada pela razão de prevalência (RP), com intervalo de confiança (IC) de 95%. Resultados: Foram registradas 555 notificações de gestantes suspeitas para a COVID-19, correspondentes a 487 mulheres. A prevalência de confirmação para a doença foi de 27,3%. O sintoma mais frequente no momento da notificação foi cefaleia (53,0%), entretanto o mais associado à confirmação foi a anosmia (RP: 2,28; IC 95%: 1,68-3,09). Das notificações registradas, 35,0% foram realizadas por gestantes que tiveram contato com casos suspeitos ou confirmados de COVID-19. O contato prévio foi mais relatado por gestantes assintomáticas, em comparação às gestantes que apresentaram sintomas (RP: 1,46; IC 95%: 1,12-1,91). Mulheres que relataram contato prévio com suspeitos ou confirmados para a COVID-19 apresentaram maior frequência de doença confirmada, quando comparadas às gestantes não expostas (RP: 1,80; IC 95%: 1,35-2,39). Conclusão: As gestantes, por terem maior susceptibilidade a surtos de doenças e gravidade do quadro, podem ter adotado com mais atenção medidas como a realização de testes diagnósticos quando em contato prévio com casos de COVID-19, mesmo assintomáticas.


Objective: To characterize the notifications of SARS-CoV-2 infection in pregnant women in a city in the South of Santa Catarina. Methods: Cross-sectional study that evaluated notifications of suspected cases of SARS-CoV-2 infection in pregnant women in the municipality of Tubarão, Santa Catarina, from March 2020 to October 2021. Data were collected from the SARS-CoV-2 infection notification forms from the Municipal Health Foundation, and from the Citizen's Electronic Health Record of the notified pregnant women. The comparison of the prevalence of confirmation according to symptoms and maternal characteristics was performed using the Prevalence Ratio (PR), with a confidence interval (CI) of 95%. Results: 555 notifications of suspected pregnant women for COVID-19 were registered, corresponding to 487 women. The prevalence of confirmation for the disease was 27.3%. The most frequent symptom at the time of notification was headache (53.0%), however, the most associated with confirmation was anosmia (PR: 2.28; 95% CI: 1.68-3.09). Of the notifications registered, 35.0% were made by pregnant women who had contact with suspected or confirmed cases of COVID-19. The previous contact was more frequently reported by asymptomatic pregnant women compared to pregnant women who had symptoms (PR: 1.46; 95% CI: 1.12-1.91). Women who reported previous contact with suspected or confirmed COVID-19 had a higher frequency of confirmed disease when compared to unexposed pregnant women (PR: 1.80; 95% CI: 1.35-2.39). Conclusion: Pregnant women, due to their greater susceptibility to disease outbreaks and disease severity, may have adopted more attentive measures such as diagnostic testing in the face of previous contact with cases of COVID-19, even if asymptomatic.


Subject(s)
Humans , Female , Pregnancy , Signs and Symptoms , Comorbidity , Diagnostic Techniques and Procedures/statistics & numerical data , Public Health Surveillance , Maternal Health , COVID-19
10.
Rev. neuro-psiquiatr. (Impr.) ; 86(1): 18-29, ene. 2023. ilus, tab
Article in Spanish | LILACS, LIPECS | ID: biblio-1442081

ABSTRACT

La Ataxia-Telangiectasia (AT) es una rara enfermedad de herencia autosómica recesiva y de afección multisistémica, caracterizada por ataxia progresiva, inmunodeficiencia variable con infecciones recurrentes, riesgo incrementado de neoplasias con o sin telangiectasias óculo-cutáneas. La AT es causada por variantes patogénicas bialélicas en el gen ATM. Su diagnóstico se basa en la sospecha de un cuadro clínico compatible, niveles elevados de alfafetoproteína, atrofia cerebelosa y estudios genéticos. No existe tratamiento curativo de AT y su manejo se basa en medidas de soporte y prevención de complicaciones y asesoramiento genético. En esta revisión, actualizamos la epidemiología, manifestaciones clínicas, diagnóstico y tratamiento de AT incluyendo una búsqueda de casos publicados en el Perú.


Ataxia-Telangiectasia (AT) is a rare autosomal recessive disease with multisystemic involvement, characterized by slowly progressive ataxia, variable immunodeficiency with recurrent infections, increased risk of neoplasms with or without oculocutaneous telangiectasias. AT is caused by biallelic pathogenic variants within the ATM gene. Its diagnosis is based on suspicion of a compatible clinical symptomatology, increased levels of alpha-fetoprotein, cerebellar atrophy, and genetic testing. There is no curative treatment for AT and its management is based on supportive and preventive measures of eventual complications and genetic counseling. This review updates the epidemiology, clinical manifestations, diagnosis, and treatment of AT, including a search for cases published in Peru.


Subject(s)
Humans , Peru , Ataxia , Signs and Symptoms , Ataxia Telangiectasia , Epidemiology , Ataxia Telangiectasia Mutated Proteins
11.
Rev. Flum. Odontol. (Online) ; 1(60): 1-14, jan.-abr. 2023. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1411180

ABSTRACT

O equilíbrio sistêmico e a saúde bucal são condições clínicas que estabelecem entre si uma relação multidimensional capaz de exercer grande impacto sobre o bem-estar cotidiano do indivíduo. As disfunções metabólicas associadas ao estado nutricional e a perda da capacidade muscular geram uma maior necessidade de cuidados em pessoas idosas. Sob o ponto de vista odontológico a presença de dentes naturais bem como o grau de doença periodontal, estão associados a competência mastigatória e, desta forma, são fatores determinantes na saúde da população acima dos 60 anos de idade. O presente estudo teve como objetivo avaliar, através da análise retrospectiva dos últimos 05 anos, a relação entre a saúde bucal e as condições sistêmicas de indivíduos acima de 60 anos residentes na Baixada Fluminense (Rio de Janeiro/Brasil) com evidente crescimento demográfico populacional. Para isso foram analisados 11.390 prontuários de pacientes usuários da Clínica Odontológica da Universidade Iguaçu/RJ sendo selecionados 1.125 que atendiam aos critérios de inclusão. Os resultados destacam a presença de doença periodontal em cerca de 56% dos indivíduos diabéticos, além de 43% com quadro hipertensivo no momento do atendimento apontando para uma importante relação entre a atenção com a saúde bucal da população assistida nessa região e suas condições sistêmicas.


Systemic balance and oral health are clinical conditions that establish a multidimensional relationship capable of having a great impact on the individual's daily well-being. Metabolic dysfunctions associated with nutritional status and loss of muscle capacity generate a greater need for care in the elderly. From the dental point of view, the presence of natural teeth, as well as the degree of periodontal disease, are associated with masticatory competence and, thus, are determining factors in the health of the population over 60 years of age. The present study aimed to describe descriptively, through the retrospective analysis of the last 05 years, the relationship between oral health and the systemic conditions of individuals over 60 years old living in the Baixada Fluminense (Rio de Janeiro / Brazil) with evident population demographic growth. For that purpose, 11,390 medical records of patients who were users of the Clínica Odontológica of Universidade Iguaçu / RJ were analyzed, 1,125 who met the inclusion criteria were selected. The results highlight the presence of periodontal disease in about 56% of diabetic individuals, in addition to 43% with the hypertensive condition at the time of care, pointing to an important relationship between the attention to the oral health of the assisted population in this region and their systemic conditions.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Signs and Symptoms , Aged , Medical Records , Oral Health , Dental Care for Aged , Delivery of Health Care
12.
San Salvador; MINSAL; ene, 16,2023. 9 p.
Non-conventional in Spanish | BISSAL, LILACS | ID: biblio-1414045

ABSTRACT

El término Covid persistente fue utilizado por primera vez por la Dra. Elisa Perego, como un hashtag de Twitter en mayo de 2020. Describía su propia experiencia de una condición cíclica multifásica, que difería de la evolución clínica característica de Covid-19 tanto en sintomatología como en tiempo. El término Covid persistente o 'Long Covid' tiene varios nombres dependiendo de la literatura consultada: 'secuelas post-agudas de Covid-19', 'Covid¬-19 en curso', 'síndrome crónico de Covid', 'Covid de larga distancia' (Long haulers) y 'condición post-Covid-19', esta última es la utilizada por la Organización Mundial de la Salud (OMS) y todas son consideradas por los Centros para el Control y la Prevención de Enfermedades (CDC) como 'condiciones pos Covid. Aún no existe consenso en cuanto al reconocimiento de Covid persistente como entidad clínica, así como tampoco en cuanto a su nombre y criterios diagnósticos. Sin embargo, dada la alta prevalencia de la sintomatología a la que se le asocia, es imperativo que los servicios y las políticas de salud prioricen su atención. A la vez, es necesario efectuar estudios a futuro para identificar en detalle los diferentes subtipos de Covid persistente y, permitir así, su atención médica estratificada sin que los servicios de salud no se vean abrumados.


The term persistent Covid was used for the first time by Dr. Elisa Perego, as a Twitter hashtag in May 2020. It described her own experience of a multiphasic cyclical condition, which differed from the characteristic clinical evolution of Covid-19 both in symptomatology as in time The term persistent Covid or 'Long Covid' has several names depending on the literature consulted: 'post-acute sequelae of Covid-19', 'Covid¬-19 in progress', 'chronic Covid syndrome', 'Long-distance Covid ' (Long haulers) and 'post-Covid-19 condition', the latter is the one used by the World Health Organization (WHO) and all are considered by the Centers for Disease Control and Prevention (CDC) as ' post covid conditions. There is still no consensus regarding the recognition of persistent Covid as a clinical entity, nor regarding its name and diagnostic criteria. However, given the high prevalence of the symptoms to which it is associated, it is imperative that health services and policies prioritize care. At the same time, it is necessary to carry out future studies to identify in detail the different subtypes of persistent Covid and, thus, allow their stratified medical care without the health services being overwhelmed.


Subject(s)
Research , COVID-19 , Signs and Symptoms , Time , Clinical Evolution , Consensus , El Salvador
13.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1518472

ABSTRACT

Objetivo: descrever o perfil clínico-epidemiológico de pacientes internados com o novo coronavírus, que evoluíram para óbito, em hospital de referência em doenças infecciosas. Método: estudo transversal, realizado em um hospital público do Estado do Ceará, Brasil, no período de janeiro a março de 2021, por meio de acesso aos 244 prontuários dos pacientes que foram internados com a COVID-19, com exame confirmatório de RT-PCR, teste rápido, sorologia ou tomografia, entre os meses de março a dezembro de 2020, e que evoluíram para óbito durante a internação hospitalar. Resultados: público formado por homens, com idade igual ou maior a 60 anos, casado/união estável, aposentado, residente na capital, com hipertensão e diabetes associadas, que foi a óbito em março e junho, em enfermaria. Os principais sinais e sintomas na internação foram saturação de oxigênio em ar ambiente menor que 92%, dispneia, síndrome respiratória aguda grave e febre; a principal indicação clínica para internação foi a insuficiência respiratória; e o principal esquema terapêutico utilizado foi uma combinação de outros antibióticos, anticoagulantes, azitromicina, corticoide e cloroquina/hidroxicloroquina. Conclusão: o estudo revela um público de homens, com mais de 60 anos de idade com dupla carga de doença crônica não transmissível


Objective: to describe the clinical-epidemiological profile of patients hospitalized with the new coronavirus, who died at a referral hospital for infectious diseases. Method: cross-sectional study, conducted in a public hospital in the State of Ceará, Brazil, from January to March 2021, through access to the 244 medical records of patients who were hospitalized with COVID-19, with confirmatory examination of RT-PCR, rapid test, serology or tomography, between March and December 2020, and who evolved to death during hospitalization. Results: public formed by men, aged 60 years or older, married/stable union, retired, residing in the capital, with associated hypertension and diabetes, who died in March and June, in the ward. The main signs and symptoms at admission, they were oxygen saturation in ambient air below 92%, dyspnea, severe acute respiratory syndrome and fever; the main clinical indication for admission was respiratory failure; and the main therapeutic regimen used was a combination of other antibiotics, anticoagulants, azithromycin, corticosteroids and chloroquine/hydroxychloroquine. Conclusion: the study reveals a population of men, over 60 years of age, with a double burden of chronic non-communicable disease


Objetivo: describir el perfil clínico y epidemiológico de los pacientes hospitalizados con el nuevo coronavirus, que evolucionaron hasta la muerte, en un hospital de referencia en enfermedades infecciosas. Método: estudio transversal, realizado en un hospital público del Estado de Ceará, Brasil, de enero a marzo de 2021, a través del acceso a las 244 historias clínicas de pacientes que fueron hospitalizados con COVID-19, con examen confirmatorio de RT-PCR, prueba rápida, serología o tomografía, entre marzo y diciembre de 2020, y que evolucionaron hasta la muerte durante la hospitalización. Resultados: público formado por hombres, de 60 años o más, casados/estables, jubilados, residentes en la capital, con hipertensión y diabetes asociada, fallecidos en marzo y junio, en la sala. Los principales signos y síntomas al ingreso fueron saturación de oxígeno en el aire ambiente inferior al 92%, disnea, síndrome respiratorio agudo severo y fiebre; la principal indicación clínica para la hospitalización fue la insuficiencia respiratoria; y el principal régimen terapéutico utilizado fue una combinación de otros antibióticos, anticoagulantes, azitromicina, corticosteroides y cloroquina/hidroxicloroquina. Conclusión: o El estudio revela una audiencia de hombres mayores de 60 años con una doble carga de enfermedades crónicas no transmisibles


Subject(s)
Humans , Male , Female , Signs and Symptoms , Drug Therapy , COVID-19 , Hospitalization
14.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1524028

ABSTRACT

Objetivo: investigar o conhecimento de mulheres atendidas na Atenção Primária sobre a detecção precoce do câncer de mama. Método: estudo de abordagem quantitativa e transversal, realizado com 265 mulheres em idade de rastreamento mamográfico. A coleta foi realizada presencialmente com instrumento validado Breast Cancer Awareness Measure. Resultados: verificou-se que há, de um modo geral, conhecimento sobre os sinais clínicos para o câncer de mama, no entanto há desconhecimento sobre a idade preconizada para realização do exame, e não houve consenso sobre os fatores hereditários para o câncer de mama. A dificuldade de marcar a consulta e a falta de transporte foram apontadas como barreiras que dificultam a procura de profissionais de saúde. Considerações finais: torna-se fundamental fortalecer as ações para a detecção precoce do câncer de mama, com produção e disseminação do conhecimento e provimento de subsídios que garantam o acesso rápido e facilitado às iniciativas de rastreamento e diagnóstico precoce


Objectives: to investigate the knowledge of women assisted in Primary Care about early detection of breast cancer. Method: quantitative and cross-sectional study, conducted with 265 women in age for mammographic screening. The collection was performed face-to-face with a validated Breast Cancer Awareness Measure instrument. Results: it was found that there is, in general, knowledge about the clinical signs of breast cancer, however there is lack of knowledge about the recommended age for the examination, and there was no consensus about the hereditary factors for breast cancer. The difficulty in making appointments and the lack of transportation were pointed out as barriers that hinder the search for health professionals. Conclusion: it is essential to strengthen actions for early detection of breast cancer, with production and dissemination of knowledge and provision of subsidies to ensure rapid and easy access to screening and early diagnosis initiatives


Objetivos: investigar el conocimiento de las mujeres atendidas en Atención Primaria sobre la detección precoz del cáncer de mama. Método: estudio con enfoque cuantitativo y transversal, realizado con 265 mujeres en edad de tamizaje mamografico. La recolección se realizó de manera presencial con un instrumento validado Breast Cancer Awareness Measure. Resultados: se constató que existe, en general, conocimiento sobre los signos clínicos para el cáncer de mama, sin embargo, existe desconocimiento sobre la edad recomendada para la realización del examen, y no hubo consenso sobre los factores hereditarios para el cáncer de mama. La dificultad para hacer una cita y la falta de transporte fueron identificadas como barreras que dificultan la búsqueda de profesionales de la salud. Conclusión: es fundamental fortalecer las acciones para la detección temprana del cáncer de mama, con la producción y difusión de conocimiento y la provisión de subsidios que garanticen el acceso rápido y fácil a las iniciativas de tamizaje y diagnóstico temprano


Subject(s)
Humans , Female , Signs and Symptoms , Breast Neoplasms , Early Diagnosis , Primary Health Care
15.
Rev. cuba. pediatr ; 952023. ilus, tab
Article in Spanish | LILACS, CUMED | ID: biblio-1515280

ABSTRACT

Introducción: Las manifestaciones clínicas de la COVID-19 se presentan con particularidades diferentes en cada momento epidemiológico. Objetivo: Examinar las características clínicas de pacientes en edad pediátrica con COVID-19 durante la fase aguda de hospitalización, en diferentes momentos epidemiológicos. Métodos: Estudio descriptivo, transversal realizado en la provincia de Cienfuegos. Se estudiaron 784 pacientes diagnosticados con COVID-19, entre marzo de 2020 y marzo de 2022. Se analizaron las variables: edad, sexo, procedencia, antecedentes patológicos personales, sintomatología inicial, clasificación clínica, complicaciones, estadía, evolución y momento epidemiológico. Resultados: Los niños más hospitalizados fueron los menores de cinco años (57 por ciento) con un discreto predominio del sexo femenino (52 por ciento). El 71 por ciento de la muestra no presentó comorbilidades. La forma sintomática de la enfermedad se manifestó en 57 por ciento de los pacientes, y la asintomática en 42 por ciento. Solo 1 por ciento presentó formas graves de la infección. El mayor porcentaje de casos sintomáticos se produjo en el momento epidemiológico en el cual prevaleció la cepa Ómicron. La fiebre, la tos, y la secreción nasal fueron, por ese orden, las manifestaciones clínicas predominantes. El 4 por ciento presentó neumonías, y hubo un fallecido en la serie. El 67 por ciento egresó después de una estadía entre uno, y seis días. Conclusiones: Se comprobaron diferencias en el comportamiento clínico de la COVID-19, en sus diferentes momentos epidemiológicos en Cienfuegos. La forma de presentarse la infección por SARS-CoV-2 puede ser similar a otras infecciones respiratorias virales. Esto requiere mantener la vigilancia de esta enfermedad en niños(AU)


Introduction: The clinical manifestations of COVID-19 are presented with different particularities at each epidemiological moment. Objective: To examine the clinical characteristics of pediatric patients with COVID-19 during the acute phase of hospitalization, at different epidemiological times. Methods: A descriptive, cross-sectional study was conducted in the province of Cienfuegos. 784 patients diagnosed with COVID-19 between March 2020 and March 2022 were studied. The following variables were analyzed: age, sex, origin, personal pathological history, initial symptomatology, clinical classification, complications, stay, evolution and epidemiological moment. Results: The most hospitalized children were children under five years of age (57 percent) with a slight predominance of females (52 percent). 71 percent of the sample had no comorbidities. The symptomatic form of the disease manifested itself in 57 percent of patients, and the asymptomatic in 42 percent . Only 1 percent had severe forms of the infection. The highest percentage of symptomatic cases occurred at the epidemiological moment in which the Ómicron strain prevailed. Fever, cough, and runny nose were, in that order, the predominant clinical manifestations. 4 percent of the patients had pneumonia, and there was one death in the series. 67 percent discharged after a stay of one to six days. Conclusions: Differences were found in the clinical behavior of COVID-19, in its different epidemiological moments in Cienfuegos. The way SARS-CoV-2 infection occurs may be similar to other viral respiratory infections. This requires maintaining surveillance for this disease in children(AU)


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Signs and Symptoms , Comorbidity , COVID-19/epidemiology , Epidemiology, Descriptive , Cross-Sectional Studies , Retrospective Studies
16.
Health sci. dis ; 24(1): 101-108, 2023. figures, tables
Article in English | AIM | ID: biblio-1411298

ABSTRACT

Objectifs. Décrire les aspects cliniques, bactériologiques et évolutifs du sepsis et du choc septique dans le service de réanimation polyvalente du CHUB. Patients et méthodes. Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. Les variables épidémiologiques, cliniques, bactériologiques et évolutives ont été analysées avec Excel 2019. Résultats. 56 patients ont été retenus (20,7%). Leur âge moyen était de 43,1 ± 17,9 ans (extrêmes de 18 et 84 ans), avec 66,1% des hommes. Le foyer infectieux initial était péritonéal (64,3 %). À l'admission, le nombre médian de défaillances d'organes par patient était de trois (maximum 5). Les défaillances rénale (71,4%), hépatique (69,6%) et hémodynamique (62,5%) étaient les plus représentées. Le taux de réalisation du bilan bactériologique était de 35,7% : hémoculture (10,7%), uroculture (14,3%), porte d'entrée infectieuse (7,1%). La durée d'hospitalisation des patients sortis vivants était de 8,1 ± 6,3 jours (extrêmes de 2 et 31 jours). Le taux de mortalité était de 57,1%. Les décès survenaient au-delà de 24 h d'hospitalisation (75%), chez des patients avec comorbidités (65,6%), porte d'entrée péritonéale (59,4%), et défaillances hémodynamique (81,2%) et rénale (75%). Conclusion. Les prévalences du sepsis et du choc septique dans notre série sont superposables à celles de la littérature. Le taux de réalisation des bilans bactériologiques reste faible. La mortalité du sepsis demeure très élevée.


Introduction. No accurate data on sepsis and septic shock in intensive care unit (ICU) in the Republic of Congo are available. The aim of the study was to describe the course of patients with sepsis and/or septic shock in the polyvalent ICU of the University Teaching Hospital of Brazzaville. Patients and methods. This was a cross-sectional, monocentric and descriptive study, lasting 12 months, including patients aged at least 18 years admitted to ICU for sepsis or septic shock. The clinical presentation, the bacteriological findings and the outcome were analyzed with Excel 2019. Results. 56 patients were selected (20.7%). The average age was 43.1 ± 17.9 years (extremes 18 and 84 years), with 66.1% of men. The initial infection was peritoneal (64.3%). At admission, the median number of organ failures per patient was three (maximum 5). Renal (71.4%), hepatic (69.6%) and hemodynamic (62.5%) failures were the most common. Bacteriological assessment rate was 35.7%: blood culture (10.7%), urine culture (14.3%). The duration of hospitalization of alive patients was 8.1 ± 6.3 days (extremes 2 and 31 days). The mortality rate was 57.1%. Deaths occurred beyond 24 hours of hospitalization (75%), in patients with comorbidities (65.6%), peritonitis (59.4%), hemodynamic (81.2%) and renal (75%) failures. Conclusion. The prevalence of sepsis and septic shock in our study is comparable to other published series. The bacteriological assessments rate is still low. The mortality is very high.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Shock, Septic , Bacteriology , Sepsis , Emergency Medical Services , Anesthesia Department, Hospital , Signs and Symptoms , Prevalence
17.
Health sci. dis ; 24(2 Suppl 1): 26-30, 2023. figures, tables
Article in French | AIM | ID: biblio-1416528

ABSTRACT

Background. The COVID-19 pandemic has added an additional burden in countries with already fragile health systems. Our objective was to determine the prevalence and seroprevalence of COVID-19 in suspected malaria during the second wave in Yaounde. Methods. A descriptive cross-sectional study was conducted at the Jordan Medical Services for 8 weeks from April 19 to June 13, 2021, i.e., during the second wave in Cameroon. For the 86 patients with suspected malaria, nasopharyngeal and blood samples were taken for SARS-CoV-2 antigen and anti-SARS-CoV-2 IgG and IgM using the STANDARD TM Q COVID-19 Ag kit from SD BIOSENSOR, Korea, 2020 and Standard TM Q COVID 19 Ac IgG/IgM kit from SD BIOSENSOR, Korea, 2020 respectively. Confirmation of malaria was done by microscopic examination of stained blood smears. Results. Malaria was confirmed in 20.9% (18) of cases. The prevalences of COVID-19 and COVID-19/malaria co-infection were 8.1% and 0.9% respectively. Of the 25.6% (54) of patients with anti-COVID-19 IgM, no positive microscopic cases were found. On the other hand, a little more than half of the patients had IgG antibodies against COVID-19 whether they had a positive thick drop or not (56.0% (42/75) and 52.2% (71/136) respectively). Conclusion. In case of suspicion of malaria in a malaria area, it seems important to consider COVID-19 as a differential diagnosis.


Introduction. La pandémie de la COVID-19 a ajouté un fardeau supplémentaire dans les pays aux systèmes de santé déjà fragiles. Objectif : déterminer la prévalence et la séroprévalence de la COVID-19 en cas de suspicion du paludisme au cours de la deuxième vagueà Yaoundé. Méthodologie. Une étude transversale descriptive a été menée au Centre Médical le Jourdain pendant 8 semaines du 19 Avril au 13 Juin 2021 soit durant la deuxième vague au Cameroun. Pour les 86 patients avec suspicion de paludisme, des prélèvements nasopharyngé et sanguins ont été réalisés pour la recherche d'antigène du SRAS- CoV 2 et des IgG et IgM anti-SARS-CoV-2 grâce aux kits STANDARDTM Q COVID-19 Ag de SD BIOSENSOR, Corée, 2020 et StandardTM Q COVID 19 Ac IgG/IgM de SD BIOSENSOR, Corée, 2020 respectivement. La confirmation du paludisme a été faite grâce à l'examen microscopique des étalements de sang colorés. Résultats. Le paludisme était confirmé dans 20,9% (18) des cas. Les prévalences de la COVID-19 et de la coïnfection COVID19/Paludisme étaient de 8,1% et de 0,9% respectivement. Sur les 25,6% (54) des patients avec des IgM anti-COVID-19, aucun cas de microscopie positive n'a été retrouvé. Par ailleurs un peu plus de la moitié des patients avaient des anticorps IgG anti-COVID-19 qu'ils aient une goutte épaisse positive ou pas soit 56,0% (42/75) et 52,2% (71/136) respectivement. Conclusion. En cas de suspicion du paludisme en zone impaludée, il parait non négligeable de considérer la COVID-19 comme un diagnostic différentiel.


Subject(s)
Humans , Male , Female , Signs and Symptoms , COVID-19 , Malaria , Therapeutics , Prevalence , Coinfection , SARS-CoV-2
18.
Pan Afr. med. j ; 45(NA): NA-NA, 2023. tables
Article in English | AIM | ID: biblio-1433890

ABSTRACT

Introduction: controlling the worldwide pandemic, coronavirus disease (COVID-19), could be impossible due to the hesitancy about the available vaccines and the difficulty to implement strict restrictions. Little information is available about herd immunity in the highly vulnerable region of North East Africa, Egypt. Objectives: to assess the seroprevalence of SARS-CoV-2 during the pandemic in one of the highly vulnerable populations in Egypt, Fayoum district of Fayoum Governorate. Additionally, to assess the predictive value of symptoms and other associated risk factors towards a positive COVID-19 test. Methods: in this cross-sectional community-based pilot study, immunoglobulin G (IgG) antibodies that are specific for the SARS-CoV-2 spike (S1-RBD) protein were tested during the period from February 2021 to July 2021. Results: out of 155 participants, 60.6% were SARS-CoV-2 seropositive. Out of symptomatic and asymptomatic individuals, 76.5% and 56.2% were seropositive, respectively. Surprisingly, only one individual had received the COVID-19 vaccine. Previous history of COVID-19; such as symptoms and gender are statistically significant predictors of high seroconversion independent of age, comorbidities, and level of education. Conclusion: this study which disclosed unexpectedly high SARS-CoV-2 seroconversion among the Egyptians, might provide a clear insight into COVID-19 transmission patterns and state of immunity. Further study with a larger sample size on a large scale is required to represent the whole local population.


Subject(s)
Humans , Male , Female , Risk Factors , Coronavirus , Seroconversion , SARS-CoV-2 , COVID-19 , Signs and Symptoms , Cross-Sectional Studies , Antibodies
19.
Ghana Med. J. (Online) ; 57(2): 97-101, 2023. tables
Article in English | AIM | ID: biblio-1436154

ABSTRACT

Objective: This study aimed to determine the duration of SARS-CoV-2 clearance in persons in Ghana. The research question was whether the duration of virus clearance in Ghana matched the 14 days recommended by the World Health Organization (WHO); this had direct implications for transmission, which was key in managing the COVID-19 pandemic. Design: This was a retrospective analytical study. Setting: All facilities that submitted clinical specimens to Noguchi Memorial Institute for Medical Research (NMIMR) for SARS-CoV-2 diagnosis between March to June 2020 were included in the study. Interventions: Samples from 480 persons who tested positive for SARS-CoV-2 by RT-PCR from March to June 2020 at NMIMR and submitted at least two follow-up samples were retrospectively analysed. Individuals with two consecutive negative RT-PCR retesting results were considered to have cleared SARS-CoV-2. Results: The median time from the initial positive test to virus clearance was 20 days (IQR: 5-56 days). This was six days longer than the WHO-recommended 14 days, after which infected persons could be de-isolated. Sputum and nasopharyngeal swabs proved more sensitive for detecting viral RNA as the infection progressed. At a significance level of 0.05, age and sex did not seem to influence the time to SARS-CoV-2 clearance. Conclusions: The median time to SARS-CoV-2 clearance in this study was 20 days, suggesting that SARS-CoV-2 infected persons in Ghana take longer to clear the virus. This finding calls for further investigations into whether patients who remain PCR positive continue to be infectious and inform isolation practices in Ghana.


Subject(s)
Humans , Male , Female , Signs and Symptoms , Middle East Respiratory Syndrome Coronavirus , SARS-CoV-2 , COVID-19 , COVID-19 Nucleic Acid Testing
20.
PAMJ One Health ; 11(NA): 1-16, 2023. figures, tables
Article in English | AIM | ID: biblio-1452522

ABSTRACT

Introduction: the COVID-19 pandemic had prompted governments in many countries to enact laws and policies to combat the spread of COVID-19 at work. The DEL required every worker to be screened when they arrived at work. Screening methods included self-reporting symptoms using a symptom monitoring tool. This study aimed to determine compliance with the symptom monitoring tool by assessing the knowledge, attitude, and practice of the MHSF employees. Methods: a cross-sectional questionnaire was administered to the employees. Information related to demographic, COVID-19 exposure, knowledge of COVID-19 and the symptom monitoring tool, attitude towards the symptom monitoring tool and practices towards COVID-19 and the symptom monitoring tool was collected. Results: a total of 90 participants participated in the study. The majority (N=45; 50%) of respondents were aged between 30 and 39 years old, with more female (N=50) than male (N=40) participants. The majority (N=51; 56.7%) only had grade 12 as the highest level of education. There were 25% (N=10) of males and 20% (N=10) of females who contracted COVID-19. The relationship between the COVID-19 positive cases and the symptom monitoring tool identifying symptoms had a strong negative correlation (-0.932). Respondent's knowledge of COVID-19 and the symptom monitoring tool was moderate (72.4%), with the attitude to the symptom monitoring tool being moderate (63.3%) as well. However, the practices of the COVID-19 guidelines and the symptom monitoring tool were good (93.3%).


Subject(s)
Diagnosis , Military Health , COVID-19 , Signs and Symptoms , Mass Screening
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